Phenotype Database is a collection of open source projects that work together as a data warehouse for bioinformatics data, specifically '*omics' data.
It consists of a hub project, the General Study Capture Framework, and several spoke projects ('modules') that contain various types of biological
... [More] data. The components communicate via HTTP JSON messages.
Phenotype Database is a project supported by various organizations and networks, a.o. the European Nutrigenomics Organisation, Netherlands Metabolomics Centre and Netherlands Bioinformatics Centre. [Less]
tranSMART is an OSS for translational research. The tranSMART Foundation (www.transmartfoundation.org) coordinates the community that is developing around the tranSMART platform.
LabKey Server is open source software that helps scientists manage, analyze and share complex datasets. It supports tandem mass spectrometry, flow cytometry, assays for neutralizing antibodies, Luminex, observational studies, and secure, web-based collaboration.
The software is modular
... [More], configurable, and customizable. Written in Java, it can be installed in your institution on any modern hardware and operating system. It is designed to integrate with your existing systems, instruments, and work flows, and to be readily adapted by skilled programmers to novel methods of inquiry.
The project is under active development by a team of professional software engineers and a community of active contributors. We release new versions about four times per year. [Less]
BioMart is a query-oriented data management system developed jointly by the European Bioinformatics Institute (EBI) and Cold Spring Harbor Laboratory (CSHL).
The system can be used with any type of data and comes with a range of query interfaces and administration tools, including 'out of the
... [More] box' website that can be installed, configured and customised according to requirements. The system simplifies the task of creation and maintenance of advanced query interfaces backed by a relational database and it is particularly suited for providing the 'data mining' like searches of complex descriptive (e.g. biological) data. BioMart can work with existing data repositories by converting them to a required BioMart format as well as newly created databases. [Less]
The Distributed Annotation System (DAS) defines a communication protocol used to exchange biological sequence annotations. DAS is a client-server system in which a single client integrates data from multiple servers.
Data distribution, performed by DAS servers, is separated from visualization
... [More], which is done by DAS clients. Little coordination is needed among the various information providers.
DAS is heavily used in the genome bioinformatics community for sharing information about gene and protein sequences as well as protein structures. [Less]
Adun currently includes tools for the calculation and analysis of several dynamic properties of macromolecules. Several force fields have already been implemented (Enzymix, Charmm and AMBER) and a sophisticated distributed database of simulations results that can be directly accessed by the program
... [More] is in development. Simulations methods currently include Newtonian and Langevin molecular dynamics. [Less]
QuteMol is an open source (GPL), interactive, high quality molecular visualization system. QuteMol exploits the current GPU capabilities through OpenGL shaders to offers an array of innovative visual effects. QuteMol visualization techniques are aimed at improving clarity and an easier understanding
... [More] of the 3D shape and structure of large molecules or complex proteins.
* Real Time Ambient Occlusion
* Depth Aware Silhouette Enhancement
* Ball and Sticks, Space-Fill and Liquorice visualization modes
* High resolution antialiased snapshots for creating publication quality renderings
* Automatic generation of animated gifs of rotating molecules for web pages animations
* Interactive rendering of large molecules and protein (>100k atoms)
* Standard PDB input [Less]
Pysam is a python module for reading and manipulating Samfiles. It's a lightweight wrapper of the samtools C-API. Pysam also includes an interface for tabix.
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