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FastAPI is a modern, fast (high-performance), web framework for building APIs with Python 3.6+ based on standard Python type hints.

GINO - GINO Is Not ORM - is an extremely simple Python ORM, using SQLAlchemy core to define table models, and asyncpg to interact with database. GINO tries to stay in the middle between ORM and non-ORM: GINO operates database rows with "plain old Python objects" - a rollback doesn't magically ... [More] change their values. Any database operations are explicit. There are no dirty models, no sessions, no magic. You have concrete control to the database, through a convenient object interface. GINO depends on asyncpg, which means it works only for PostgreSQL and asyncio, so Python 3.6 is required. Based on SQLAlchemy, gate to its ecosystem is open - feel free to use e.g. Alembic to manage your schema changes. And we specially designed a few candies for the Sanic server. [Less]

Starlette is a lightweight ASGI framework/toolkit, which is ideal for building high performance asyncio services.